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Merck pill under review as US alerted over rising cases, new variant of COVID-19


Nepalnews
2021 Nov 27, 17:10, NEW YORK
Pedestrians walk by a holiday installation on a street in New York, the United States, Nov. 23, 2021. (Photo via XINHUA)

Global health leaders are urging caution as the holiday season is underway in Western countries, pointing to a 23 percent spike in coronavirus cases across the Americas in the past week, a surge that follows spikes in Europe, which officials warn could be a "window into the future for the Americas," media reported.

U.S. health regulators are expected to make public on Friday a staff review about the COVID-19 pill molnupiravir from Merck & Co. and Ridgeback Biotherapeutics LP, with an analysis of clinical-trial data for the drug included, according to The Wall Street Journal.

The companies said that the pill reduces the risk of hospitalization and dying in people at high risk of severe COVID-19 infections. The report may also provide the staff's opinion about whether health authorities should clear the drug for use. Britain cleared molnupiravir for use earlier this month.

Molnupiravir, together with another experimental antiviral from Pfizer Inc. which is also under review by the U.S. Food and Drug Administration (FDA), promises to fill a big gap in COVID-19 treatment for a pill that people could easily take at home to keep them out of the hospital, according to the report.

CASES UP, INOCULATIONS DOWN:

"Coronavirus cases are on the rise nationally, an unwelcome trend after leveling off earlier this fall," reported The Washington Post (WP) on Thursday. On Monday, the White House reported a seven-day daily average of just under 93,000 cases, an 18 percent jump from a week earlier. Hospitalizations rose 6 percent to 5,600 per day.

At least two dozen states have seen cases rise at least 5 percent in the past two weeks, with Michigan, Minnesota, New Mexico, New Hampshire and North Dakota each recording per capita jumps of more than 60 percent. Some highly vaccinated states, including Vermont and Massachusetts, were also seeing steep rises in cases.



People wait for COVID-19 tests on Times Square in New York, the United States, Nov. 23, 2021. (photo via Xinhua)
People wait for COVID-19 tests on Times Square in New York, the United States, Nov. 23, 2021. (photo via Xinhua)

"The growing caseload across the country has raised the specter of another surge this winter -- what would be the nation's fifth," said the report. Expert opinions vary, but Amber D'Souza, a professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health, was quoted as saying that a surge seems imminent.

Following the initial peak of COVID-19 vaccine uptake among healthcare personnel (HCP) in the U.S. hospital system in early 2021, rates quickly decreased in the second half of the year -- currently, as much as 30 percent of HCP remain unvaccinated, reported Medical News Today, a web-based outlet for medical information and news.

"Data analysis from the Department of Health and Human Services (HHS) Unified Hospital Data Surveillance System from January-September 2021, collected from over 3.3 million HCP across 2,086 hospitals, found that as many as 30 percent of workers were unvaccinated," said the report.

HCP working in children's hospitals had the highest vaccination rates at 77 percent. Critical access hospitals had vaccination rates of 64 percent. Hospitals in metropolitan counties had the highest vaccination rate of 71 percent for HCP, followed by rural counties (65.1 percent), and non-metropolitan rural counties (63.3 percent).

FUTURE WINDOW, IMMINENT MENACE:

Global health leaders are urging caution as the holiday season is underway in Western countries, pointing to a 23 percent spike in coronavirus cases across the Americas in the past week, a surge that follows spikes in Europe, which officials warn could be a "window into the future for the Americas," reported WP on Thursday.


Travelers are seen at LaGuardia Airport in New York, the United States, Nov. 24, 2021. (photo via Xinhua)
Travelers are seen at LaGuardia Airport in New York, the United States, Nov. 24, 2021. (photo via Xinhua)

"Time and again, we've seen how the infection dynamics in Europe are mirrored here several weeks later," Carissa Etienne, director of the Pan American Health Organization, said during a Wednesday briefing. "The future is unfolding before us, and it must be a wake-up call for our region because we are even more vulnerable."

On the same day, Director General of the World Health Organization (WHO) Tedros Adhanom Ghebreyesus expressed concern about a "false sense of security that vaccines have ended the pandemic and that people who are vaccinated do not need to take any other precautions." "No country or region is out of the woods," he said.

Meanwhile, an increasing number of countries, including Britain, France, Israel, Italy and Singapore, were moving on Friday to restrict travel from South Africa and other countries in the region, a day after South African authorities identified a concerning new coronavirus variant with mutations that one scientist said marked a "big jump in evolution."

"In the past, governments have taken days, weeks or months to issue travel restrictions in response to new variants. This time, restrictions came within hours of South Africa's announcement, and hours before health officials from the country began discussing the variant with the WHO," reported The New York Times on Friday.

The governments of Croatia, Malta, the Netherlands and Japan also announced on Friday that they would impose similar restrictions. Markets were down in Japan in response to the variant's discovery, and officials in Australia and New Zealand said that they were monitoring it closely, according to the report.

READ ALSO:

US COVID-19 US coronavirus new cases US coronavirus updates US COIVID Death Toll US COVID Active cases US COVID-19 Tally MoHP US total coronavirus cases Merck Pill
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